Just testing Houdini muscles speed with mid settings

Muscle pass 30 min (20 coll pass,1000 const inter) muscl remesh (min 0.007 - max 0.013)
Tissue pass 3 hs ( 600 const inter,max tet size 0.039)
Skin pass 30 min (300 const iter,3 substeps) sin remesh min (0.006-masx 0.01)

Karma Xpu render 250 frames - 3hs

Rig:5950x 64gb 4090