Hello. I don't know if this is even possible; I've looked all over, and tried unsuccessfully to have a skull and chain, collide with this cloth; can someone please help? I'd appreciate a revelation or two, thank you in advance, I've attached a screenshot of my setup

What do you mean by collide? If you want the skull to fall into the cloth like an RBD object, for instance, the one way might be to add it as an RBD object to vellumsolver1’s internal dopnet. Another way might be to add a shapematch constraint to the skull and pack it together with the cloth as another vellum object, like this guy did: https://www.youtube.com/watch?v=0O-fX6dZIgM [www.youtube.com]